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Diffstat (limited to 'academic/bwa/README')
| -rw-r--r-- | academic/bwa/README | 16 |
1 files changed, 10 insertions, 6 deletions
diff --git a/academic/bwa/README b/academic/bwa/README index fe07da7e2d..a77a28a8e4 100644 --- a/academic/bwa/README +++ b/academic/bwa/README @@ -1,10 +1,14 @@ Burrows-Wheeler Aligner (BWA) is an efficient program that aligns -relatively short nucleotide sequences against a long reference -sequence such as the human genome. It implements two algorithms, bwa- -short and BWA-SW. The former works for query sequences shorter than -200bp and the latter for longer sequences up to around 100kbp. Both -algorithms do gapped alignment. They are usually more accurate and -faster on queries with low error rates. +relatively short nucleotide sequences against a long reference sequence +such as the human genome. It implements two algorithms, bwa-short and +BWA-SW. The former works for query sequences shorter than 200bp and the +latter for longer sequences up to around 100kbp. Both algorithms do +gapped alignment. They are usually more accurate and faster on queries +with low error rates. + +A configuration file ("_aptx_configuration_file") will be used if it is +in your $HOME. An example configuration file is available in +/usr/share/archeopteryx. If you use BWA-SW, please cite: Li H. and Durbin R. (2010) Fast and accurate long-read alignment with |